Article
Association of the CYP17 gene and CYP19 gene polymorphisms with risk of endometriosis in Japanese women.
Human reproduction (Oxford, England) - 1 Apr 2002
Kado Noriko, Kitawaki Jo, Obayashi Hiroshi, Ishihara Hiroaki, Koshiba Hisato, Kusuki Izumi, Tsukamoto Katsumi, Hasegawa Goji, Nakamura Naoto, Yoshikawa Toshikazu, Honjo Hideo
Abstract excerpt
BACKGROUND: To investigate whether polymorphisms of CYP17 and CYP19 genes are associated with the risk of endometriosis, we analysed the frequency and distribution of a single nucleotide polymorphism at the 5' untranslated region of the CYP17 gene, and a tetranucleotide (TTTA) tandem repeat polymorphism and a 3 bp insertion (I)/deletion (D) polymorphism in intron 4 of the CYP19 gene. METHODS: We studied 140...
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