Article
Screening of a panel of steroid-related genes showed polymorphisms of aromatase genes confer susceptibility to advanced stage endometriosis in the Taiwanese Han population.
Taiwanese journal of obstetrics & gynecology - 1 Dec 2013
Wu Cheng-Hsuan, Yang Jyuer-Ger, Chang Yu-Jun, Hsu Chao-Chin, Kuo Pao-Lin
Abstract excerpt
OBJECTIVE: To establish a multilocus model for studying the effect of steroid-related genes on advanced stage endometriosis. MATERIALS AND METHODS: A total of 121 patients with advanced stage endometriosis and 171 control women were included. Eighteen single-nucleotide polymorphisms (SNPs) from nine genes (HSD17B1, HSD17B2, HSD17B5, HSD17B6, CYP17, CYP19, ERα, ERβ, and PGR) were genotyped using the TaqMan assays....
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