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Article

Variants in the alpha-Methylacyl-CoA racemase gene and the association with advanced distal colorectal adenoma.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Aug 2007

Daugherty Sarah E, Platz Elizabeth A, Shugart Yin Yao, Fallin M Daniele, Isaacs William B, Chatterjee Nilanjin, Welch Robert, Huang Wen-Yi, Hayes Richard B

Abstract excerpt

BACKGROUND: alpha-Methylacyl-CoA racemase (AMACR), an enzyme involved in oxidation of branched chain fatty acids and cholesterol metabolites, as well as ibuprofen metabolism, is overexpressed in colorectal adenomas and cancer. AMACR gene variants have been associated with hereditary prostate cancer, but no studies have evaluated their etiologic role in colorectal carcinogenesis. METHODS: We conducted a...

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PMID: 17684125
DOI: 10.1158/1055-9965.EPI-07-0117

Genes

AMACR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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