Article
Polymorphic variants in alpha-methylacyl-CoA racemase and prostate cancer.
The Prostate - 1 Oct 2007
Daugherty Sarah E, Shugart Yin Yao, Platz Elizabeth A, Fallin M Daniele, Isaacs William B, Pfeiffer Ruth M, Welch Robert, Huang Wen-Yi, Reding Douglas, Hayes Richard B
Abstract excerpt
BACKGROUND: Alpha-methylacyl-CoA racemase (AMACR), which prepares branched chain fatty acids to be metabolized for energy and is implicated in the activation of the COX-inhibiting form of ibuprofen, is overexpressed in prostate cancer and its precursor lesions. Significant differences in AMACR al...
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