Article
ApolipoproteinA1-75 G/A (M1-) polymorphism and lipoprotein(a); anti- vs. pro-Atherogenic properties.
Lipids in health and disease - 6 Aug 2007
Albahrani Ali I, Usher Jannete J, Alkindi Mohammed, Marks Eileen, Ranganath L, Al-yahyaee Said
Abstract excerpt
BACKGROUND: ApolipoproteinA1 (apoA1) is the major apoprotein constituent of high-density-lipoprotein(HDL). The relationship of apoA1 -75 bp(M1-) allele polymorphism with lipoprotein phenotype and cardiovascular disease (CVD) remain unclear. Overnight fasting blood samples were collected from a cohort of high-risk Omani population, 90 non-diabetic subjects and 149 type 2 diabetes mellitus (T2DM) subjects for...
Topics
- Adenine
- Apolipoprotein A-I
- Atherosclerosis
- Gene Frequency
- Genetic Carrier Screening
- Genetic Predisposition to Disease
- Genotype
- Guanine
- Homozygote
- Humans
- Lipoprotein(a)
- Polymorphism, Genetic
- Polymorphism, Single Nucleotide
- Promoter Regions, Genetic