Article
Effect of apolipoprotein A1 genetic polymorphisms on lipid profiles and the risk of coronary artery disease.
Diagnostic pathology - 16 Jul 2015
Liao BiHong, Cheng KeQi, Dong ShaoHong, Liu HuaDong, Xu ZhengLei
Abstract excerpt
BACKGROUND: The disorder of lipid metabolism and genetic predisposition are major risk factors for coronary artery disease (CAD). Variants in the apolipoprotein A1 (APOA1) gene play an important role in the regulation of lipids. The objective of the present study was to investigate the effect of two polymorphisms (-75 G/A and +83 C/T) of APOA1 on lipid profiles and the risk of CAD. METHODS: A total number of 300...
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