Article
Comparison of lipid profiles with APOA1 MspI polymorphism in obese children with hyperlipidemia.
In vivo (Athens, Greece) - 1 Jan 2000
Toptas Bahar, Görmüş Uzay, Ergen Arzu, Gürkan Hakan, Keleşoglu Fatih, Darendeliler Feyza, Bas Firdevs, Dalan Altay Burak, Izbirak Güldal, Isbir Turgay
Abstract excerpt
BACKGROUND: Obesity is a multifactorial, chronic disorder leading to adverse metabolic effects on plasma lipid levels. Apolipoprotein AI (Apo AI) is the major structural component of high-density lipoprotein (HDL) and is involved in the esterification of cholesterol as a cofactor of lecithin-cholesterol acyltransferase (LCAT) and thus plays a major role in cholesterol efflux from peripheral cells. The APOA1 gene...
Topics
- Adolescent
- Alleles
- Apolipoprotein A-I
- Base Sequence
- Child
- Deoxyribonuclease HpaII
- Female
- Gene Frequency
- Genotype
- Humans
- Hyperlipidemias
- Lipids
- Male
- Molecular Sequence Data
- Obesity