Article
Gender-specific associations of the APOA1 -75G>A polymorphism with several metabolic syndrome components in Turkish adults.
Clinica chimica acta; international journal of clinical chemistry - 20 Apr 2014
Coban Neslihan, Onat Altan, Guclu-Geyik Filiz, Komurcu-Bayrak Evrim, Can Gunay, Erginel-Unaltuna Nihan
Abstract excerpt
BACKGROUND: Variations in the apolipoprotein A-1 (APOA1) gene, a determinant of plasma high-density lipoprotein cholesterol (HDL-C) and apoA-I levels, may contribute to cardiovascular diseases. We evaluated the effects of a promoter polymorphism (-75G>A) in the APOA1 gene on metabolic syndrome (MetS) components in a Turkish population sample. METHODS: Randomly selected 1515 Turkish adults (age 49.9±11.8 years,...
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