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Article

The Mediterranean paradox for susceptibility factors in coronary heart disease extends to genetics.

Annals of human genetics - 1 Jan 2008

Lao Oscar, Dupanloup Isabelle, Barbujani Guido, Bertranpetit Jaume, Calafell Francesc

Abstract excerpt

The incidence of coronary heart disease (CHD) shows a North to South gradient in Europe. We tested whether that gradient could be accounted for by the distribution of putative susceptibility genotypes. We correlated the published frequencies of susceptibility genotypes for the genes most often associated with CHD (ACE, AGT, APOE, F2, F5, MTHFR, PON1, and SERPINE1) with the incidence of the disease, controlling...

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Source

Identifiers

PMID: 17683517
DOI: 10.1111/j.1469-1809.2007.00387.x

Genes

ACE
AGT
APOE
MTHFR
PON1
SERPINE1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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