Article
Common genetic polymorphisms and coronary heart disease.
Seminars in vascular medicine - 1 Aug 2002
Keavney Bernard
Abstract excerpt
Susceptibility to coronary heart disease (CHD) is to some extent genetically determined, but despite a great deal of effort, in the past decade research has shown little progress towards identifying the genetic variants responsible. This article explores the reasons why this is so, using the ACE insertion/deletion polymorphism, which has been the most extensively studied of all genetic polymorphisms with respect...
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