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Article

Structure of the peripheral arm of a minimalistic respiratory complex I.

Structure (London, England : 1993) - 6 Jan 2022

Schimpf Johannes, Oppermann Sabrina, Gerasimova Tatjana, Santos Seica Ana Filipa, Hellwig Petra, Grishkovskaya Irina, Wohlwend Daniel, Haselbach David, Friedrich Thorsten

Abstract excerpt

Respiratory complex I drives proton translocation across energy-transducing membranes by NADH oxidation coupled with (ubi)quinone reduction. In humans, its dysfunction is associated with neurodegenerative diseases. The Escherichia coli complex represents the structural minimal form of an energy-converting NADH:ubiquinone oxidoreductase. Here, we report the structure of the peripheral arm of the E. coli complex I...

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Identifiers

PMID: 34562374
DOI: 10.1016/j.str.2021.09.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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