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Article

Bone morphogenetic protein signaling is essential for terminal differentiation of the intestinal secretory cell lineage.

Gastroenterology - 1 Sept 2007

Auclair Benoit A, Benoit Yannick D, Rivard Nathalie, Mishina Yuji, Perreault Nathalie

Abstract excerpt

BACKGROUND & AIMS: Bone morphogenetic proteins (Bmps) are morphogens known to play key roles in gastrointestinal development and pathology. Most Bmps are produced primarily by the mesenchymal compartment and activate their signaling pathways following a paracrine or autocrine route. The aim of this study was to investigate the role of epithelial Bmp signaling in intestinal morphogenesis and maintenance of adult...

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Identifiers

PMID: 17678919
DOI: 10.1053/j.gastro.2007.06.066

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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