Article
A functional circuit underlying male sexual behaviour in the female mouse brain.
Nature - 30 Aug 2007
Kimchi Tali, Xu Jennings, Dulac Catherine
Abstract excerpt
In mice, pheromone detection is mediated by the vomeronasal organ and the main olfactory epithelium. Male mice that are deficient for Trpc2, an ion channel specifically expressed in VNO neurons and essential for VNO sensory transduction, are impaired in sex discrimination and male-male aggression. We report here that Trpc2-/- female mice show a reduction in female-specific behaviour, including maternal aggression...
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