Article
Altered sexual and social behaviors in trp2 mutant mice.
Proceedings of the National Academy of Sciences of the United States of America - 30 Apr 2002
Leypold Bradley G, Yu C Ron, Leinders-Zufall Trese, Kim Michelle M, Zufall Frank, Axel Richard
Abstract excerpt
We have used gene targeting to generate mice with a homozygous deficiency in trp2, a cation channel expressed in the vomeronasal organ (VNO). Trp2 mutant animals reveal a striking reduction in the electrophysiological response to pheromones in the VNO, suggesting that trp2 plays a central role in...
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