Article
Loss of sex discrimination and male-male aggression in mice deficient for TRP2.
Science (New York, N.Y.) - 22 Feb 2002
Stowers Lisa, Holy Timothy E, Meister Markus, Dulac Catherine, Koentges Georgy
Abstract excerpt
The mouse vomeronasal organ (VNO) is thought to mediate social behaviors and neuroendocrine changes elicited by pheromonal cues. The molecular mechanisms underlying the sensory response to pheromones and the behavioral repertoire induced through the VNO are not fully characterized. Using the tools of mouse genetics and multielectrode recording, we demonstrate that the sensory activation of VNO neurons requires...
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