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Article

Chromosome-specific and noisy IFNB1 transcription in individual virus-infected human primary dendritic cells.

Nucleic acids research - 1 Jan 2007

Hu Jianzhong, Sealfon Stuart C, Hayot Fernand, Jayaprakash Ciriyam, Kumar Madhu, Pendleton Audrey C, Ganee Arnaud, Fernandez-Sesma Ana, Moran Thomas M, Wetmur James G

Abstract excerpt

The induction of interferon beta (IFNB1) is a key event in the antiviral immune response. We studied the role of transcriptional noise in the regulation of the IFNB1 locus in primary cultures of human dendritic cells (DCs), which are important 'first responders' to viral infection. In single cell...

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Share to Chromosomes, Human
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17675303
DOI: 10.1093/nar/gkm557
PMCID: PMC1976463

Genes

IFNB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17675303-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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