Gene-based SNP mapping of a psychotic bipolar affective disorder linkage region on 22q12.3: association with HMG2L1 and TOM1.

doi:10.1002/ajmg.b.30574

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Article

Gene-based SNP mapping of a psychotic bipolar affective disorder linkage region on 22q12.3: association with HMG2L1 and TOM1.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jan 2008

Potash James B, Buervenich Silvia, Cox Nancy J, Zandi Peter P, Akula Nirmala, Steele Jo, Rathe Jennifer A, Avramopoulos Dimitrios, Detera-Wadleigh Sevilla D, Gershon Elliot S, DePaulo J Raymond, Feinberg Andrew P, McMahon Francis J

Abstract excerpt

Genetic linkage studies in both bipolar affective disorder (BPAD) and schizophrenia have implicated overlapping regions of chromosome 22q. We previously reported that BPAD pedigrees containing multiple members with psychotic symptoms showed suggestive linkage to chromosome 22q12.3. Now we have tested 189 single nucleotide polymorphisms (SNPs) spanning a 3 Mb region around the linkage peak for association with...

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PMID: 17671966
DOI: 10.1002/ajmg.b.30574

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TOM1

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