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Article

Growth of transgenic RAF-induced lung adenomas is increased in mice with a disrupted PPARbeta/delta gene.

International journal of oncology - 1 Sept 2007

Müller-Brüsselbach Sabine, Ebrahimsade Schokufe, Jäkel Jörg, Eckhardt Jenny, Rapp Ulf R, Peters Jeffrey M, Moll Roland, Müller Rolf

Abstract excerpt

Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors with essential functions in regulating lipid metabolism. Both the PPARbeta (also referred to as PPARdelta) and PPARgamma subtype have been reported to either attenuate or potentiate tumorigenesis in a number of different models of intestinal and skin carcinogenesis. In the present study, we have addressed the role of...

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Source

Identifiers

PMID: 17671688

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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