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Article

The CNR1 gene as a pharmacogenetic factor for antipsychotics rather than a susceptibility gene for schizophrenia.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Jan 2008

Hamdani Nora, Tabeze Jean-Pierre, Ramoz Nicolas, Ades Jean, Hamon Michel, Sarfati Yves, Boni Claudette, Gorwood Philip

Abstract excerpt

Neurobiological research suggests a significant role of the endocannabinoid system in schizophrenia vulnerability and also in the quality of response to antipsychotics. Genetics offer an opportunity to disentangle its involvement in the disease vulnerability vs an influence on antipsychotics' effects. The possible role of a tag SNP (the 1359G/A polymorphism) of the gene encoding the cannabinoid receptor type 1...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Polymorphism, Genetic

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Share to Receptor, Cannabinoid, CB1

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Source

Identifiers

PMID: 17669634
DOI: 10.1016/j.euroneuro.2007.05.005

Genes

CNR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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