Article
Cannabinoid receptor 1 gene (CNR1) and susceptibility to a quantitative phenotype for hebephrenic schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Apr 2008
Chavarría-Siles Iván, Contreras-Rojas Javier, Hare Elizabeth, Walss-Bass Consuelo, Quezada Paulina, Dassori Albana, Contreras Salvador, Medina Rolando, Ramírez Mercedes, Salazar Rodolfo, Raventos Henriette, Escamilla Michael A
Abstract excerpt
Functional alterations of components of the endogenous cannabinoid system, in particular of the cannabinoid receptor 1 protein (CB1), are hypothetical contributors to many of the symptoms seen in schizophrenia. Variants within the cannabinoid receptor 1 gene (CNR1) have been shown to be directly associated with the hebephrenic form of schizophrenia in a Japanese population. This finding, however, has yet to be...
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