Article
Genetic association analysis of CNR1 and CNR2 polymorphisms with schizophrenia in a Korean population.
Psychiatric genetics - 1 Oct 2014
Bae Joon Seol, Kim Jason Yongha, Park Byung-Lae, Kim Jeong-Hyun, Kim Bomi, Park Chul Soo, Kim Bong-Jo, Lee Cheol-Soon, Lee Migyung, Choi Woo Hyuk, Shin Tae-Min, Hwang Jaeuk, Shin Hyoung Doo, Woo Sung-Il
Abstract excerpt
Located on 6q15 and 1p36.11, cannabinoid receptor 1 (CNR1) and cannabinoid receptor 2 (CNR2) genes are considered to be a positional and functional candidate gene for the development of mental disorders such as schizophrenia because CNR1 is known as a regulator of dopamine signaling in the hippocampus and the cerebral cortex. However, few genetic studies have been carried out to investigate an association of CNR1...
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