Article
Characterization of the insulin-like growth factor axis and Wilms' tumour suppressor gene in hyperparathyroidism.
The British journal of surgery - 1 Oct 2007
Wong C K M, Lai T, White S, Sheffield E, Wheeler M H, Stewart C E H, Farndon J R
Abstract excerpt
BACKGROUND: Genetic mutations and upregulation of growth factors are implicated in the pathogenesis of hyperparathyroidism. The aim of this study was to evaluate the role of Wilms' tumour suppressor gene (WT-1) and the insulin-like growth factor (IGF) axis in hyperparathyroidism. METHODS: The expression of WT-1 and IGF components was examined by immunohistochemistry, reverse transcriptase-polymerase chain...
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