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Article

HIV-1 TAR element is processed by Dicer to yield a viral micro-RNA involved in chromatin remodeling of the viral LTR.

BMC molecular biology - 30 Jul 2007

Klase Zachary, Kale Prachee, Winograd Rafael, Gupta Madhur V, Heydarian Mohammad, Berro Reem, McCaffrey Timothy, Kashanchi Fatah

Abstract excerpt

BACKGROUND: RNA interference (RNAi) is a regulatory mechanism conserved in higher eukaryotes. The RNAi pathway generates small interfering RNA (siRNA) or micro RNA (miRNA) from either long double stranded stretches of RNA or RNA hairpins, respectively. The siRNA or miRNA then guides an effector complex to a homologous sequence of mRNA and regulates suppression of gene expression through one of several mechanisms....

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Identifiers

PMID: 17663774
DOI: 10.1186/1471-2199-8-63
PMCID: PMC1955452

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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HIV-1 TAR element is processed by Dicer to yield a viral micro-RNA involved in chromatin remodeling of the viral LTR.PMID 17663774Read ↗

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