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Article

Inhibition of transcription by the TAR RNA of HIV-1 in a nuclear extract of HeLa cells.

Nucleic acids research - 1 Sept 1997

Yamamoto R, Koseki S, Ohkawa J, Murakami K, Nishikawa S, Taira K, Kumar P K

Abstract excerpt

Regulation of transcription of human immunodeficiency virus type-1 (HIV-1) requires specific interaction of Tat protein with the trans-activation response region (TAR). Inhibition of replication of HIV-1 has previously been achieved with a TAR decoy, namely a short RNA oligonucleotide that corresponded to the sequence of the authentic TAR RNA. Since TAR RNA has the potential to interact with cellular factors, we...

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Identifiers

PMID: 9254702
DOI: 10.1093/nar/25.17.3445
PMCID: PMC146900

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Inhibition of transcription by the TAR RNA of HIV-1 in a nuclear extract of HeLa cells.PMID 9254702Read ↗

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