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The PTPN22 promoter polymorphism -1123G>C association cannot be distinguished from the 1858C>T association in a Norwegian rheumatoid arthritis material.

Tissue antigens - 1 Sept 2007

Viken M K, Olsson M, Flåm S T, Førre O, Kvien T K, Thorsby E, Lie B A

Abstract excerpt

The protein tyrosine phosphatase nonreceptor 22 (PTPN22) gene has, during the last 2 years, been recognized as a susceptibility gene for numerous autoimmune diseases, including rheumatoid arthritis (RA) and type 1 diabetes. An association between the exonic 1858C>T single nucleotide polymorphism (SNP) and RA has repeatedly been replicated in several Caucasian populations. The SNP is not associated with autoimmune...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17661906
DOI: 10.1111/j.1399-0039.2007.00871.x

Genes

PTPN22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The PTPN22 promoter polymorphism -1123G>C association cannot be distinguished from the 1858C>T association in a Norwegian rheumatoid arthritis material.PMID 17661906Read ↗

A PTPN22 promoter polymorphism -1123G>C is associated with RA pathogenesis in Chinese.Semantic proximity Read ↗

1858 C/T polymorphism of the protein tyrosine phosphatase nonreceptor 22 gene and rheumatoid arthritis risk in europeans: a meta-analysis.Semantic proximity Read ↗

Meta-analysis reveals PTPN22 1858C/T polymorphism confers susceptibility to rheumatoid arthritis in Caucasian but not in Asian population.Semantic proximity Read ↗

Association of PTPN22 1858T/T genotype with type 1 diabetes, Graves' disease but not with rheumatoid arthritis in Russian population.Semantic proximity Read ↗

Association of the PTPN22 gene (-1123G > C) polymorphism with rheumatoid arthritis in Chinese patients.Semantic proximity Read ↗

PTPN22 1858 C/T polymorphism is associated with alteration of cytokine profiles as a potential pathogenic mechanism in rheumatoid arthritis.Semantic proximity Read ↗

Haplotype analysis revealed no association between the PTPN22 gene and RA in a Japanese population.Semantic proximity Read ↗

Finnish case-control and family studies support PTPN22 R620W polymorphism as a risk factor in rheumatoid arthritis, but suggest only minimal or no effect in juvenile idiopathic arthritis.Semantic proximity Read ↗

Effects of PTPN22 C1858T polymorphism on susceptibility and clinical characteristics of British Caucasian rheumatoid arthritis patients.Semantic proximity Read ↗

The association between the PTPN22 C1858T polymorphism and rheumatoid arthritis: a meta-analysis update.Semantic proximity Read ↗

[PTPN22 1858C/T polymorphism is associated with rheumatoid arthritis susceptibility in Caucasian population: a meta-analysis].Semantic proximity Read ↗

PTPN22 1858C>T polymorphism is strongly associated with rheumatoid arthritis but not with a response to methotrexate therapy.Semantic proximity Read ↗

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