Article
Meta-analysis reveals PTPN22 1858C/T polymorphism confers susceptibility to rheumatoid arthritis in Caucasian but not in Asian population.
Autoimmunity - 1 Jan 2016
Nabi Gowher, Akhter Naseem, Wahid Mohd, Bhatia Kanchan, Mandal Raju Kumar, Dar Sajad Ahmad, Jawed Arshad, Haque Shafiul
Abstract excerpt
The PTPN22 1858C/T polymorphism is associated with rheumatoid arthritis (RA). However, reports from the Asian populations are conflicting in nature and lacks consensus. The aim of our study was to evaluate the association between the PTPN22 1858C/T polymorphism and RA in Asian and Caucasian subjects by carrying out a meta-analysis of Asian and Caucasian data. A total of 27 205 RA cases and 27 677 controls were...
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