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Article

The association between the PTPN22 C1858T polymorphism and rheumatoid arthritis: a meta-analysis update.

Molecular biology reports - 1 Apr 2012

Lee Young Ho, Bae Sang-Cheol, Choi Sung Jae, Ji Jong Dae, Song Gwan Gyu

Abstract excerpt

The aim of this study was to determine whether the protein tyrosine phosphatase nonreceptor 22 (PTPN22) C1858T polymorphism confers susceptibility to rheumatoid arthritis (RA) in populations with different ethnicities. A meta-analysis was conducted on the PTPN22 C1858T polymorphism involving eighteen studies, which in total contained 20344 RA patients and 21828 controls. Meta-analysis revealed an association...

Topics

Alleles
Arthritis, Rheumatoid
Confidence Intervals
Ethnicity
Gene Frequency
Genetic Association Studies
Genetic Heterogeneity
Genetic Predisposition to Disease
Humans
Odds Ratio
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Prevalence

Protein Tyrosine Phosphatase, Non-Receptor Type 22

Publication Bias

Source

Identifiers

PMID: 21706348
DOI: 10.1007/s11033-011-1117-3

Genes

PTPN22

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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The association between the PTPN22 C1858T polymorphism and rheumatoid arthritis: a meta-analysis update.PMID 21706348Read ↗

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