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Article

A PTPN22 promoter polymorphism -1123G>C is associated with RA pathogenesis in Chinese.

Rheumatology international - 1 Mar 2012

Huang Jian-Jun, Qiu Yu-Rong, Li Hai-Xia, Sun De-Hua, Yang Jia, Yang Chun-Li

Abstract excerpt

The minor allele of the non-synonymous single nucleotide polymorphism (SNP) +1858C>T within the PTPN22 gene has now been unequivocally confirmed as conferring susceptibility to RA in population from Europe and America, but not in population from Asia. The aim of this study was to jointly address and integrate these separate findings to further elucidate the association between the PTPN22 gene and RA in Chinese...

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Share to Arthritis, Rheumatoid
Share to Asian People
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression

Share to Genetic Predisposition to Disease

Share to Polymorphism, Single Nucleotide

Share to Promoter Regions, Genetic

Share to Protein Tyrosine Phosphatase, Non-Receptor Type 22

Source

Identifiers

PMID: 21193990
DOI: 10.1007/s00296-010-1705-x

Genes

PTPN22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A PTPN22 promoter polymorphism -1123G>C is associated with RA pathogenesis in Chinese.PMID 21193990Read ↗

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