Investigation of the C-terminal redox center of high-Mr thioredoxin reductase by protein engineering and semisynthesis.

Abstract excerpt

High-molecular weight thioredoxin reductases (TRs) catalyze the reduction of the redox-active disulfide bond of thioredoxin, but an important difference in the TR family is the sequence of the C-terminal redox-active tetrapeptide that interacts directly with thioredoxin, especially the presence or absence of a selenocysteine (Sec) residue in this tetrapeptide. In this study, we have employed protein engineering...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Caenorhabditis elegans
• Share to Electron Transport