Article
Regeneration mechanisms of Arabidopsis thaliana methionine sulfoxide reductases B by glutaredoxins and thioredoxins.
The Journal of biological chemistry - 10 Jul 2009
Tarrago Lionel, Laugier Edith, Zaffagnini Mirko, Marchand Christophe, Le Maréchal Pierre, Rouhier Nicolas, Lemaire Stéphane D, Rey Pascal
Abstract excerpt
Methionine oxidation leads to the formation of S- and R-diastereomers of methionine sulfoxide (MetSO), which are reduced back to methionine by methionine sulfoxide reductases (MSRs) A and B, respectively. MSRBs are classified in two groups depending on the conservation of one or two redox-active Cys; 2-Cys MSRBs possess a catalytic Cys-reducing MetSO and a resolving Cys, allowing regeneration by thioredoxins. The...
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