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Article

Lumbar disc disease shows linkage to chromosome 19 overlapping with a QTL for hand OA.

Annals of the rheumatic diseases - 1 Jan 2008

Williams F M K, Kato B S, Livshits G, Sambrook P N, Spector T D, MacGregor A J

Abstract excerpt

OBJECTIVE: Cervical and lumbar degenerative disc disease (CDD and LDD, respectively) form part of the spine osteoarthritis (OA) phenotype and are known to be influenced by genetic factors. A genome-wide linkage analysis was performed to identify new chromosomal regions of interest. METHODS: Dizygotic healthy female twin volunteers (n = 348) from the TwinsUK register who had magnetic resonance imaging scans 10...

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Identifiers

PMID: 17660224
DOI: 10.1136/ard.2007.073262

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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