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Article

Linkage analysis of chromosome 2q in osteoarthritis.

Rheumatology (Oxford, England) - 1 Apr 2000

Loughlin J, Mustafa Z, Smith A, Irven C, Carr A J, Clipsham K, Chitnavis J, Bloomfield V A, McCartney M, Cox O, Sinsheimer J S, Sykes B, Chapman K E

Abstract excerpt

BACKGROUND: In independent linkage studies chromosome 2q11-q24 and chromosome 2q23-35 have previously been implicated as regions potentially harbouring susceptibility loci for osteoarthritis (OA). OBJECTIVE: To test chromosome 2q for linkage to idiopathic osteoarthritis. METHODS: Using a cohort of 481 OA families that each contained at least one affected sibling pair with severe end-stage disease (ascertained by...

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Identifiers

PMID: 10817769
DOI: 10.1093/rheumatology/39.4.377

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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