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Article

Associations between genetic factors, tobacco smoking and autoantibodies in familial and sporadic rheumatoid arthritis.

Annals of the rheumatic diseases - 1 Apr 2008

Michou L, Teixeira V H, Pierlot C, Lasbleiz S, Bardin T, Dieudé P, Prum B, Cornélis F, Petit-Teixeira E

Abstract excerpt

OBJECTIVES: The objective of this study was to investigate the association between genes (HLA-DRB1 and PTPN22) and tobacco smoking, separately as well as combined, and serological markers of rheumatoid arthritis (RA) in a French population with RA. METHODS: 274 patients with RA with half of them belonging to RA multicase families, were genotyped for HLA-DRB1 allele and for PTPN22-1858 polymorphism. IgM rheumatoid...

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Share to Arthritis, Rheumatoid
Share to Autoantibodies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HLA-DR Antigens

Share to HLA-DRB1 Chains

Share to Peptides, Cyclic

Share to Protein Tyrosine Phosphatase, Non-Receptor Type 22

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Source

Identifiers

PMID: 17660221
DOI: 10.1136/ard.2007.075622

Genes

PTPN22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Associations between genetic factors, tobacco smoking and autoantibodies in familial and sporadic rheumatoid arthritis.PMID 17660221Read ↗

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