Article
Mannose-binding lectin polymorphisms and pulmonary outcome in premature neonates: a pilot study.
Intensive care medicine - 1 Oct 2007
Capoluongo Ettore, Vento Giovanni, Rocchetti Sandro, Giardina Emiliano, Concolino Paola, Sinibaldi Cecilia, Santonocito Concetta, Vendettuoli Valentina, Tana Milena, Tirone Chiara, Zuppi Cecilia, Romagnoli Costantino, Novelli Giuseppe, Giardina Bruno, Ameglio Franco
Abstract excerpt
OBJECTIVE: Mannose-binding lectin (MBL2) is a collectin molecule able to activate the complement system and the subsequent inflammatory mechanisms. Several MBL2 genetic variants have been described, including the six variants studied in this report, which are those analyzed in most detail in the medical literature. DESIGN: The present study analyzes the prevalence of MBL2 gene variants in preterm newborns and...
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