Article
Association between bronchopulmonary dysplasia and MBL2 and IL1-RN polymorphisms.
Pediatrics international : official journal of the Japan Pediatric Society - 1 Dec 2012
Cakmak Bilin Cetinkaya, Calkavur Sebnem, Ozkinay Ferda, Koroglu Ozge Altun, Onay Huseyin, Itirli Gulcin, Karaca Emin, Yalaz Mehmet, Akisu Mete, Kultursay Nilgün
Abstract excerpt
BACKGROUND: The imbalance between pro-inflammatory and anti-inflammatory cytokines may play a role in the development of bronchopulmonary dysplasia (BPD) in preterm infants. Mannose binding lectin (MBL) codon 54 and interleukin 1 receptor antagonist gene (IL1-RN) polymorphisms cause genetic predisposition to increased risk of infection and inflammation, therefore may increase the risk of BPD. The aim of this...
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