Article
Mannose-binding lectin gene polymorphism and early neonatal outcome in preterm infants.
Neonatology - 1 Jan 2010
Koroglu Ozge Altun, Onay Huseyin, Erdemir Gulin, Yalaz Mehmet, Cakmak Bilin, Akisu Mete, Ozkinay Ferda, Kultursay Nilgun
Abstract excerpt
BACKGROUND: Mannose-binding lectin (MBL) as a component of innate immunity plays an important role in preterm infants in whom adaptive immunity is not sufficiently developed. Polymorphisms in immunoregulatory genes influence the response to infection and subsequent inflammation. Infection and inflammation have been implicated in the mechanisms responsible for many of the diseases in the preterm newborns....
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