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Article

High prevalence of mannose-binding lectin (MBL) deficiency in premature neonates.

Clinical and experimental immunology - 1 Jul 2006

Frakking F N J, Brouwer N, Zweers D, Merkus M P, Kuijpers T W, Offringa M, Dolman K M

Abstract excerpt

Mannose-binding lectin (MBL) is a component of innate immunity and thus particularly important in neonates in whom adaptive immunity is not yet completely developed. Promoter polymorphisms and structural exon-1 mutations in the MBL2 gene cause reduced or deficient MBL plasma concentrations. The aim of our study was to determine the prevalence of MBL deficiency in neonates admitted to the neonatal intensive care...

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Source

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Identifiers

PMID: 16792667
DOI: 10.1111/j.1365-2249.2006.03093.x
PMCID: PMC1942014

Genes

MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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