Article
Mannose-binding lectin genotypes are associated with shorter gestational age. An evolutionary advantage of low MBL production genotypes?
Molecular immunology - 1 Mar 2008
van de Geijn F E, Dolhain R J E M, van Rijs W, Willemsen S P, Hazes J M W, de Groot C J M
Abstract excerpt
BACKGROUND: The complement factor mannose-binding lectin (MBL) is associated with adverse pregnancy outcome. MBL serum concentrations are increased from early pregnancy onwards and depend upon several gene polymorphisms. We investigated whether MBL polymorphisms are associated with term and preterm birth, since preterm birth is the leading cause of neonatal morbidity and mortality. METHODS: MBL2 gene...
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