Are tumours angiogenesis-dependent?

doi:10.1002/path.1473

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Article

Are tumours angiogenesis-dependent?

The Journal of pathology - 1 Jan 2004

Verheul H M W, Voest E E, Schlingemann R O

Abstract excerpt

The final proof of principle that cancer patients can be effectively treated with angiogenesis inhibitors is eagerly awaited. Various preclinical in vivo experiments have proven that most tumours need new vessel formation in order to grow and to form metastases. First of all, tumours do not grow in avascular corneas until new blood vessels reach the implant. Secondly, the introduction of only one angiogenic gene...

Topics

Angiogenesis Inducing Agents
Angiogenesis Inhibitors
Capillaries
Cell Transformation, Neoplastic
Endothelial Cells
Humans
Neoplasms
Neovascularization, Pathologic
Phenotype

Source

Open in PubMed

Identifiers

PMID: 14694516
DOI: 10.1002/path.1473

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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