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Article

Estimation of German KIR Allele Group Haplotype Frequencies.

Frontiers in immunology - 1 Jan 2020

Solloch Ute V, Schefzyk Daniel, Schäfer Gesine, Massalski Carolin, Kohler Maja, Pruschke Jens, Heidl Annett, Schetelig Johannes, Schmidt Alexander H, Lange Vinzenz, Sauter Jürgen

Abstract excerpt

The impact of the highly polymorphic Killer-cell immunoglobulin-like receptor (KIR) gene cluster on the outcome of hematopoietic stem cell transplantation (HCST) is subject of current research. To further understand the involvement of this gene family into Natural Killer (NK) cell-mediated graft-versus-leukemia reactions, knowledge of haplotype structures, and allelic linkage is of importance. In this analysis,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32226430
DOI: 10.3389/fimmu.2020.00429
PMCID: PMC7080815

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