Article
Palmitoylation of POTE family proteins for plasma membrane targeting.
Biochemical and biophysical research communications - 23 Nov 2007
Das Sudipto, Ise Tomoko, Nagata Satoshi, Maeda Hiroshi, Bera Tapan K, Pastan Ira
Abstract excerpt
The POTE gene family is composed of 13 paralogs and likely evolved by duplications and remodeling of the human genome. One common property of POTE proteins is their localization on the inner aspect of the plasma membrane. To determine the structural elements required for membrane localization, we expressed mutants of different POTEs in 293T cells as EGFP fusion proteins. We also tested their palmitoylation by a...
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