Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Duplication of the paternal IGF2 allele in trisomy 11 and elevated expression levels of IGF2 mRNA in congenital mesoblastic nephroma of the cellular or mixed type.

Genes, chromosomes & cancer - 1 Oct 2007

Watanabe Naoki, Haruta Masayuki, Soejima Hidenobu, Fukushi Daisuke, Yokomori Kinji, Nakadate Hisaya, Okita Hajime, Hata Jun-ich, Fukuzawa Masahiro, Kaneko Yasuhiko

Abstract excerpt

In a metaphase comparative genomic hybridization and fluorescence in situ hybridization study of 13 congenital mesoblastic nephroma (CMN) tumors, trisomy 11 was found in seven cellular or mixed type tumors, disomy 11 with other chromosome changes in two cellular type tumors, and no chromosome changes in four classical type tumors. Reverse-transcription (RT)-PCR analysis detected the ETV6-NTRK3 fusion transcript...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 11
Share to Gene Duplication

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genomic Imprinting

Share to Insulin-Like Growth Factor II

Share to Kidney Neoplasms

Share to Oncogene Proteins, Fusion

Share to Translocation, Genetic

Share to Trisomy

Source

Identifiers

PMID: 17639583
DOI: 10.1002/gcc.20481

Genes

IGF2
CTCF
ETV6
NTRK3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Duplication of the paternal IGF2 allele in trisomy 11 and elevated expression levels of IGF2 mRNA in congenital mesoblastic nephroma of the cellular or mixed type.PMID 17639583Read ↗

Cryptic t(12;15)(p13;q26) producing the ETV6-NTRK3 fusion gene and no loss of IGF2 imprinting in congenital mesoblastic nephroma with trisomy 11: fluorescence in situ hybridization and IGF2 allelic expression analysis.Semantic proximity Read ↗

Molecular characterization of congenital mesoblastic nephroma and its distinction from Wilms tumor.Semantic proximity Read ↗

Adjunctive diagnostic tool for histopathological classification in congenital mesoblastic nephromaSemantic proximity Read ↗

Congenital mesoblastic nephroma is characterised by kinase mutations including EGFR internal tandem duplications, the ETV6-NTRK3 fusion, and the rare KLHL7-BRAF fusion.Semantic proximity Read ↗

Duplication of paternal IGF2 or loss of maternal IGF2 imprinting occurs in half of Wilms tumors with various structural WT1 abnormalities.Semantic proximity Read ↗

Mosaic allelic insulin-like growth factor 2 expression patterns reveal a link between Wilms' tumorigenesis and epigenetic heterogeneity.Semantic proximity Read ↗

ETV6–NTRK3 in congenital mesoblastic nephroma: A report of the SIOP/GPOH nephroblastoma studySemantic proximity Read ↗

Wilms tumour histology is determined by distinct types of precursor lesions and not epigenetic changes.Semantic proximity Read ↗

Expression of ETV6‐NTRK in classical, cellular and mixed subtypes of congenital mesoblastic nephromaSemantic proximity Read ↗

Blastemal Expression of Type I Insulin-Like Growth Factor Receptor in Wilms' Tumors Is Driven by Increased Copy Number and Correlates with RelapseSemantic proximity Read ↗

Nephron Progenitor But Not Stromal Progenitor Cells Give Rise to Wilms Tumors in Mouse Models with β-Catenin Activation or Wt1 Ablation and Igf2 Upregulation.Semantic proximity Read ↗

Involvement of germline DDX1-MYCN duplication in inherited nephroblastoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.