Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Blastemal Expression of Type I Insulin-Like Growth Factor Receptor in Wilms' Tumors Is Driven by Increased Copy Number and Correlates with Relapse

1 Dec 2006

Abstract excerpt

Most Wilms' tumors are of low stage, favorable histology, and have a high likelihood of cure with current multimodal therapy. Despite this, there remains a group of patients whose tumors recur for whom intensive salvage regimens result in survival of only 50%. Fitting a Cox proportional hazards model to microarray-based comparative genomic hybridization (aCGH) data on 68 Wilms' tumor samples, we identified a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Syndromes and Imprinting
Share to Prenatal Screening and Diagnostics
Share to Renal and related cancers

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17145858
DOI: 10.1158/0008-5472.can-06-1931

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Blastemal Expression of Type I Insulin-Like Growth Factor Receptor in Wilms' Tumors Is Driven by Increased Copy Number and Correlates with RelapsePMID 17145858Read ↗

Amplification and Overexpression of CACNA1E Correlates with Relapse in Favorable Histology Wilms' TumorsSemantic proximity Read ↗

Analysis by array CGH of genomic changes associated with the progression or relapse of Wilms' tumourSemantic proximity Read ↗

Subsets of Very Low Risk Wilms Tumor Show Distinctive Gene Expression, Histologic, and Clinical FeaturesSemantic proximity Read ↗

Association between long interspersed nuclear element-1 methylation levels and relapse in Wilms tumorsSemantic proximity Read ↗

Genomic profiling by whole-genome single nucleotide polymorphism arrays in Wilms tumor and association with relapse.Semantic proximity Read ↗

Increased expression of the insulin-like growth factor I receptor gene, IGF1R, in Wilms tumor is correlated with modulation of IGF1R promoter activity by the WT1 Wilms tumor gene product.Semantic proximity Read ↗

Loss of Imprinting of Insulin-Like Growth Factor-II (IGF2) Gene in Distinguishing Specific Biologic Subtypes of Wilms TumorSemantic proximity Read ↗

High‐resolution array CGH identifies common mechanisms that drive embryonal rhabdomyosarcoma pathogenesisSemantic proximity Read ↗

Gain of 1q is associated with adverse outcome in favorable histology Wilms' tumors.Semantic proximity Read ↗

Relationship Between <i>MYCN</i> Copy Number and Expression in Rhabdomyosarcomas and Correlation With Adverse Prognosis in the Alveolar SubtypeSemantic proximity Read ↗

WT1 mutation and 11P15 loss of heterozygosity predict relapse in very low-risk wilms tumors treated with surgery alone: a children's oncology group study.Semantic proximity Read ↗

Association of Chromosome 1q Gain With Inferior Survival in Favorable-Histology Wilms Tumor: A Report From the Children's Oncology Group.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.