Article
Molecular characterization of congenital mesoblastic nephroma and its distinction from Wilms tumor.
Cancer - 1 Nov 1992
Tomlinson G E, Argyle J C, Velasco S, Nisen P D
Abstract excerpt
BACKGROUND: Congenital mesoblastic nephroma (CMN) is a rare tumor of the neonatal kidney. It was once thought to be a variant of Wilms tumor that also arises from primitive renal cells. METHODS: Molecular characteristics of two CMN were studied to clarify their potential relationship to Wilms tumors. Patterns of gene expression were assayed by Northern blot hybridization analysis. Tumors were tested for loss of...
Topics
- Chromosome Mapping
- Chromosomes, Human, Pair 13
- DNA, Neoplasm
- Gene Expression
- Genes, Wilms Tumor
- Genes, myc
- Genotype
- Heterozygote
- Humans
- Infant, Newborn
- Insulin-Like Growth Factor II