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Article

Lrrk2 and chronic inflammation are linked to pallido-ponto-nigral degeneration caused by the N279K tau mutation.

Acta neuropathologica - 1 Sept 2007

Miklossy Judith, Qing Hong, Guo Jian-Ping, Yu Sheng, Wszolek Zbigniew K, Calne Donald, McGeer Edith G, McGeer Patrick L

Abstract excerpt

Mutations in the leucine-rich repeat kinase 2 gene (LRRK2) have been identified in families with autosomal dominant late-onset Parkinson disease (PD). Lrrk2 is a phylogenetically conserved, ubiquitous protein, which is constitutively expressed in various cells including neurons and glial cells of...

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Identifiers

PMID: 17639429
DOI: 10.1007/s00401-007-0230-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17639429-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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