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Article

Adrenomedullin, an autocrine/paracrine factor induced by androgen withdrawal, stimulates 'neuroendocrine phenotype' in LNCaP prostate tumor cells.

Oncogene - 17 Jan 2008

Berenguer C, Boudouresque F, Dussert C, Daniel L, Muracciole X, Grino M, Rossi D, Mabrouk K, Figarella-Branger D, Martin P-M, Ouafik L'Houcine

Abstract excerpt

Neuroendocrine (NE) differentiation in prostate cancer (CaP) has been reported to be an early marker associated with the development of androgen independence. The mechanisms by which CaP acquires NE properties are poorly understood. In this study, a putative role of adrenomedullin (AM) in the NE differentiation was investigated. The expression of AM and AM receptors (calcitonin receptor-like receptor...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Carcinoma, Neuroendocrine

Share to Neoplasms, Hormone-Dependent

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Source

Identifiers

PMID: 17637748
DOI: 10.1038/sj.onc.1210656

Genes

RAMP2
RAMP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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