Article
Adrenomedullin (AM) and AM receptor type 2 expression is up-regulated in prostate carcinomas (PC), and AM stimulates in vitro growth of a PC-derived cell line by enhancing proliferation and decreasing apoptosis rates.
International journal of oncology - 1 Dec 2004
Mazzocchi Giuseppina, Malendowicz Ludwik K, Ziolkowska Agnieszka, Spinazzi Raffaella, Rebuffat Piera, Aragona Francesco, Ferrazzi Eros, Parnigotto Pier Paolo, Nussdorfer Gastone G
Abstract excerpt
Adrenomedullin (AM) is a hypotensive peptide, that acts via the calcitonin receptor-like receptor (CRLR), whose interaction with the subtypes 2 and 3 of a family of receptor activity-modifying proteins (RAMP) gives rise to two distinct AM receptors, named AM1 and AM2 receptors. AM derives from th...
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