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Article

Optimal timing and duration of induction therapy for HIV-1 infection.

PLoS computational biology - 1 Jul 2007

Curlin Marcel E, Iyer Shyamala, Mittler John E

Abstract excerpt

The tradeoff between the need to suppress drug-resistant viruses and the problem of treatment toxicity has led to the development of various drug-sparing HIV-1 treatment strategies. Here we use a stochastic simulation model for viral dynamics to investigate how the timing and duration of the induction phase of induction-maintenance therapies might be optimized. Our model suggests that under a variety of...

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Identifiers

PMID: 17630827
DOI: 10.1371/journal.pcbi.0030133
PMCID: PMC1914372

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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