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Article

No association of the ACTN3 gene R577X polymorphism with endurance performance in Ironman Triathlons.

Annals of human genetics - 1 Nov 2007

Saunders C J, September A V, Xenophontos S L, Cariolou M A, Anastassiades L C, Noakes T D, Collins M

Abstract excerpt

Alpha-actinins are major structural components of the Z-discs in skeletal muscle. Alpha-actinin 3 is encoded by the ACTN3 gene and is expressed only in type II muscle fibres. Homozygosity for the nonsense mutation, 577X, within ACTN3 results in deficiency of alpha-actinin-3 but does not result in...

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Identifiers

PMID: 17627799
DOI: 10.1111/j.1469-1809.2006.00385.x

Genes

ACTN3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17627799-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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