ACTN3 X-allele carriers had greater levels of muscle damage during a half-ironman.

doi:10.1007/s00421-016-3507-7

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Article

ACTN3 X-allele carriers had greater levels of muscle damage during a half-ironman.

European journal of applied physiology - 1 Jan 2017

Del Coso Juan, Salinero Juan José, Lara Beatriz, Gallo-Salazar César, Areces Francisco, Puente Carlos, Herrero David

Abstract excerpt

PURPOSE: Alpha-actinin-3, encoded by the ACTN3 gene, is an actin-binding protein with an important role in myofibril contraction and muscle force output. In humans, there is a relatively common deficiency of the α-actinin-3 due to homozygosity in a polymorphism of the ACTN3 gene (R577X, rs1815739), that has been related to decreased resistance to strain during voluntary muscle contractions. The purpose of this...

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Identifiers

PMID: 27913923
DOI: 10.1007/s00421-016-3507-7

Genes

ACTN3

Variants

rs1815739

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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